Principal Engineer

Direct message the job poster from Rise Technical

Berlin – Permanent Employee, Full-Time, Hybrid working (3 days a week on site)

Excellent opportunity for an experienced Principal Engineer to step into a senior leadership role and contribute to a platform that revolutionises the diagnosis and treatment of cancer patients through cutting‑edge AI and machine learning.

As a spin‑off from one of Europe’s largest university hospitals and technical universities, this company is transforming the future of healthcare by combining state‑of‑the‑art software engineering, cloud infrastructure, and ML‑driven insights. With a collaborative, supportive culture, they are implementing technology that directly affects lives.

In this role, you will be the technical right‑hand to the CTO, shaping the company’s technical direction and core platform decisions. You will own architecture across multiple teams, remaining close to the technology, whilst influencing more than 60 engineers and helping teams deliver scalable, secure, and reliable systems.

The ideal candidate will be a master‑level engineer with deep technical breadth, excellent mentoring skills, and experience making architectural decisions that span departments. You may have held titles such as Staff Engineer, Principal Engineer, or even CTO at a smaller company. Leadership experience is valued, but a hands‑on technical expert who’s worked across teams and systems is key.

This is a fantastic opportunity to join an innovative, humanitarian company where your expertise will contribute to the innovation of healthcare at scale.

The Role

• Own and evolve the technical direction and architecture of core platforms and services
• Influence 60+ engineers across multiple teams with cross‑cutting technical decisions
• Lead adoption of best practices across cloud infrastructure, DevSecOps, MLOps, and backend architecture
• Mentor and coach senior engineers to raise engineering standards organisation‑wide
• Prototype solutions and work hands‑on to enable technical excellence across teams
• Partner with stakeholders to align engineering strategy with business and product goals
• Hybrid working (3 days a week on site)

The Person

• 10–15+ years’ experience in software engineering, with technical leadership across teams or departments
• Strong architecture and system design background in distributed, event‑driven systems
• Experience in cloud platforms (GCP preferred, AWS and/or Azure also welcome) and containerisation (Docker, Kubernetes)
• Proficiency in Python (important), with exposure to Java, Kotlin, TypeScript, and ML frameworks like PyTorch
• Ability to influence large‑scale technical decisions across engineering organisations (100+ engineers)
• Strong communicator and mentor, with a track record of driving best practices and technical excellence

Reference Number:

To apply for this role or to be considered for further roles, please click "Apply Now" or contact Abigail Lawrence at Rise Technical Recruitment.

Rise Technical Recruitment GmbH acts an employment agency for permanent roles and an employment business for temporary roles.

The salary advertised is the bracket available for this position. The actual salary paid will be dependent on your level of experience, qualifications and skill set. We are an equal opportunities employer and welcome applications from all suitable candidates

Seniority level

• Mid‑Senior level

Employment type

• Full‑time

Job function

• Engineering, Strategy/Planning, and Training
• Medical Practices, Medical Equipment Manufacturing, and Software Development

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