Junior Computational Scientist - Translational Microbiome Research (f/m/d)

Founded in 2020, mbiomics GmbH is developing microbiome-based therapeutics using a holistic TechBio platform that combines proprietary analytics and data science to advance live bacterial product (LBP) development.

We are looking for a Junior Computational Scientist to join our Research team in Munich. The role sits at the intersection of computational biology and translational drug development, and is ideal for an early‑career scientist with a PhD and hands‑on experience in biological or clinical data analysis.

JOB DESCRIPTION

Translational Analysis

• Analyze metagenomic, transcriptomic, metabolomic, and clinical biomarker data from ongoing clinical trials to support product development.
• Generate computational evidence for go/no‑go decisions at key development milestones (e.g., donor selection, formulation optimization, safety signal evaluation).
• Integrate multi‑omics datasets from patient cohorts to identify treatment‑response biomarkers and inform clinical development strategy.

Pipeline Development & Computational R&D

• Develop, validate, and maintain reproducible bioinformatics pipelines for strain‑level analysis, functional annotation, and community profiling.
• Contribute to the development of novel analytical approaches when off‑the‑shelf tools are insufficient—with mentorship from senior team members.
• Support regulatory‑grade documentation of computational methods, including traceability, version control, and reproducibility standards required for pre‑IND submissions.
• Work as part of cross‑functional project teams alongside wet‑lab scientists, clinicians, and regulatory specialists.
• Communicate analytical results clearly to both technical and non‑technical stakeholders, including for investor communications and publications.
• Provide regular progress updates and flag risks or resource needs early.

REQUIRED SKILLS AND COMPETENCIES

• PhD in computational biology, bioinformatics, microbiology, or a related quantitative field.
• Proficiency in Python or R for data analysis, and comfort with Unix/Linux environments.
• Hands‑on experience analyzing high‑throughput sequencing data (metagenomics, transcriptomics, or similar).
• Demonstrated ability to go beyond running existing tools—e.g., adapting methods, writing custom scripts to solve non‑standard analytical problems.
• Strong data visualization skills and the ability to present complex results in an accessible way.
• Eagerness to learn about drug development, regulatory requirements, and translational science.

PREFERRED SKILLS/ABILITIES

• Experience with microbial community analysis (compositional data, strain‑level methods, functional annotation).
• Familiarity with a workflow manager (e.g., Nextflow, Snakemake) or cloud computing platforms (GCP, AWS).
• Exposure to clinical or regulated environments (e.g., clinical trial data, IND preparation, GxP‑adjacent work).
• Experience with immunological or host‑response datasets (flow cytometry, organoids, host transcriptomics).
• Prior industry experience or internship in biotech/pharma.

ENVIRONMENT AT MBIOMICS

• Experience the unique dynamics and spirit of a biotech start‑up
• Our team? A colorful mix of international talents, humor and brilliant minds.
• We offer flexible working hours and 30 days of vacation.
• Benefits include our job ticket offer, free coffee, fruit and candy and regular team‑events.