PhD position in Molecular Cancer Biology

Chair of Biochemistry and Molecular biology

Organisation/Company UNI WUERZBURG Department Chair of Biochemistry and Molecular biology Research Field Biological sciences » Biology Researcher Profile First Stage Researcher (R1) Positions PhD Positions Country Germany Application Deadline 15 Feb 2026 - 09:00 (Europe/Berlin) Type of Contract Temporary Job Status Full-time Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

Offer Description

The research group of Prof. Dimitrios Papadopoulos at the University of Würzburg investigates RNA-based mechanisms of tumor maintenance (Papadopoulos et al. Molecular Cell 2022, 2024).

We are currently looking for an ambitious PhD candidate with an outstanding background in Biochemistry. The position is funded by the UbiQancer CRC/TRR 387 and University core funding. The project will be carried out in the vibrant Biocenter of the University of Würzburg (biozentrum.uni-wuerzburg.de/en/molbio).

The succesful candidate will characterize first-of-their-kind proteolysis targeting chimera (PROTAC) compounds in colorectal cancer cells.

We offer:

• Cutting-edge, well-funded research projects.
• Training in state-of-the-art compound screening assays, including HiBiT and ternary complex formation assays.
• Training in the performance and bioinformatic analysis of modern sequencing techniques such as CLIP-seq and TT-seq.
• Appointment for a minimum of 3 years with a competitive salary (TV-L E13).
• Hands-on supervision with internal skill building seminars.
• Close collaboration with leading experts in medicinal chemistry, molecular and structural biology.
• Enrolment in the Graduate School of Life Science, which offers a wide range of skill building courses.
• Excellent networking opportunities within the University of Würzburg, the Mildred Scheel Early Career Center and the UbiQancer consortium.

Your profile:

• Excellent MSc degree in biochemistry, or a related field.
• Wet-lab experience in one of these fields.
• Fluency in written/spoken English (minimum C1 level), knowledge of German is not required.
• Prior experience in compound screening assays, such as HiBiT is highly advantageous.

We welcome applications from suitably qualified people regardless of race, gender or disability. The University aims to increase the proportion of female employees, therefore applications from qualified women are particularly welcome. Preference will be given to people with disabilities in the case of otherwise equal aptitude.

Applications must contain a CV, a one-page letter of motivation, relevant degree certificates and academic transcripts as well as contact details of two references (one of the referees must be the MSc thesis supervisor).

Please send the documents as a single PDF file via email to: