Postdoctoral Researcher OR PhD students in Molecular Signaling Pathways in Myogenesis and Neuro[...]

Postdoctoral Researcher OR PhD students in Molecular Signaling Pathways in Myogenesis and Neuromuscular Junction (NMJ) at Friedrich-Alexander University (FAU), Germany

Position: Ph.D. Student

Deadline: 31 January 2026

Employment Start Date: 1 March 2026

Country: Germany

Research Project Overview

This project aims to elucidate the role of molecular signaling pathways in muscle development, regeneration, and NMJ function, with a special focus on the Hippo signaling pathway. The selected candidate will employ a combination of cutting‑edge techniques to investigate cellular mechanisms and their future implications for neuromuscular diseases.

Responsibilities

• Investigate the molecular and cellular mechanisms involved in myogenesis and NMJ function with a focus on the Hippo signaling pathway.
• Perform in vivo analyses using transgenic mouse models, including histological, molecular, and functional characterization.
• Conduct immunohistochemistry, immunofluorescence, and 3D microscopy to visualize cellular signaling and structural changes.
• Apply multi‑omics approaches (e.g., transcriptomics) to identify key regulatory factors in muscle and NMJ biology, with a focus on understanding their role in disease.
• Utilize genetic tools and CRISPR/Cas9 technology to manipulate specific genes involved in myogenesis and signaling.
• Collaborate with interdisciplinary teams and contribute to the overall development of the research project.

Requirements

• A Ph.D. OR M.Sc. in molecular biology, cell biology, or a related field.
• Strong background in cellular and molecular biology, with experience in in‑vivo studies (preferably cultured primary cells and mouse models).
• Expertise in techniques such as Western blotting, RT‑qPCR, immunohistochemistry, and microscopy (e.g., ZEISS, ZEN, Fiji).
• Familiar with multi‑omics approaches, including transcriptomics (experience is a plus, but motivated candidates willing to learn are encouraged).
• Experience with genetic manipulation techniques such as CRISPR/Cas9 is advantageous.
• Strong analytical skills and the ability to work both independently and collaboratively in a dynamic research environment.
• Excellent communication skills in English (knowledge of German is not required).

What We Offer

• An exciting, cutting‑edge research project with a focus on molecular signaling and muscle biology.
• Access to state‑of‑the‑art facilities and resources at FAU and through DFG‑funded collaborations.
• A supportive and dynamic research team within a highly interdisciplinary environment.
• Opportunities for professional development, including training in advanced experimental techniques.
• A competitive salary based on the standard DFG scale.

Application Process

Interested candidates should submit a CV, a brief cover letter, and the contact details of two references to In the cover letter, please outline your experience, research interests, and motivation for applying to this particular project (one‑page specific project proposals).

AI‑generated applications will be detected by specific algorithms and disregarded.

91054 Erlangen, Germany