Senior Director, Global Marketing

Mineralys Therapeutics is a clinical‑stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit

Mineralys is a fully remote company.

Senior Director, Global Marketing

Reporting to the Chief Commercial Officer, the Senior Director, Global Marketing will lead the development and execution of the ex‑U.S. commercial strategy, ensuring alignment with U.S. commercial objectives and optimizing long‑term global revenue potential.

Key Responsibilities

Global Commercial Strategy (Ex‑U.S.)

• Lead global (ex‑U.S.) market identification, prioritization, and segmentation across key geographies.
• Develop and execute go‑to‑market strategies tailored by geography and indication.
• Define optimal pathways to market entry, including indication prioritization.

Cross‑Functional Leadership

• Partner closely with Clinical and Regulatory teams to shape development programs that align with commercial objectives and regulatory requirements.
• Influence clinical study design and sequencing to maximize global commercial opportunity.
• Ensure alignment across stakeholders to maintain a unified strategy.
• Partner with Market Access to evaluate pricing and reimbursement dynamics across international markets, including health technology assessment environments.
• Identify and mitigate risks related to international reference pricing and Most Favored Nation implications.

Business Development & Partnerships

• Lead business development efforts to identify, evaluate, and secure strategic partners for market entry.
• Structure and support partnership models (e.g., licensing, co‑promotion, regional partnerships).
• Manage partner strategy to ensure successful execution in priority markets.

Strategic Analytics & Decision‑Making

• Conduct rigorous market assessments, including epidemiology, competitive landscape, and access dynamics.
• Develop commercial forecasts and scenario analyses to inform prioritization and investment decisions.
• Provide strategic recommendations to senior leadership based on data‑driven insights.

Required Experience

• 10+ years of biopharmaceutical commercial experience, including global or ex‑U.S. marketing.
• Demonstrated success in multi‑market strategy development and execution.
• Strong experience in chronic disease markets; cardiovascular experience preferred.
• Proven ability to collaborate with clinical and regulatory teams to shape development programs.
• Experience in early‑stage or pre‑market environments (Phase II or earlier strongly preferred).
• Track record of business development and partnership execution.

Capabilities & Skills

• Exceptional analytical and strategic thinking skills, particularly in market access and pricing dynamics.
• Deep understanding of global reimbursement systems and HTA bodies (e.g., Europe, Japan).
• Strong ability to navigate complex trade‑offs between global and U.S. commercial strategies.
• Excellent cross‑functional leadership and influence skills.
• Ability to operate effectively in a fast‑paced, emerging biotech environment.

Travel

• This position requires up to 20% travel. Frequent travel is outside the local area and overnight.

Compensation & Benefits

• US Salary Range: $250,000 – $265,000
• Standard company benefits: medical, dental, vision, time off, 401(k).
• Participation in Mineralys incentive plans contingent on achievement of personal and company performance.