Staff Scientist / Postdoc – Tissue Clearing & 3D Image Analysis

Stellenbeschreibung:

Overview

The Institute for Stroke and Dementia Research (ISD) at LMU Klinikum is a highly collaborative, international team at the interface between LMU and Helmholtz Munich. Our mission is to understand complex biology in 3D by combining tissue clearing, light-sheet microscopy, high-throughput analysis, and AI.

We are hiring a Staff Scientist – Tissue Clearing & Image Analysis (m/f/d) within the Mesoscale Hub of the DFG-funded Excellence Cluster SyNergy (Systems Neurology).

The role at a glance

This is a scientist role with a strong science-enabler and project-driver focus. You will run and evolve our tissue clearing + light-sheet imaging pipeline, support and manage collaborations across SyNergy, and translate complex data into robust, quantitative insight. In addition, you will contribute scientifically to a defined topic aligned with the Mesoscale Hub (with co-authorship on resulting publications).

What you’ll do

Implement tissue-clearing projects in collaborative projects within the SyNergy Excellence Cluster
Support data analysis and visualization
Drive methods development
Develop new analysis pipelines in collaboration with our AI team
Lab support: maintenance of cutting-edge light-sheet microscopes
(Optional) Support with writing new animal experiment licenses
Contribute scientifically to a defined topic aligned with the Mesoscale Hub (co-authorship on resulting publications)

What we’re looking for

Strong background in tissue clearing and/or fluorescence microscopy
Hands-on experience with light-sheet systems and 3D imaging workflows
Proficiency with Imaris and/or arivis Vision4D; experience with BigStitcher (or similar) for large volumes
Practical knowledge of atlas registration and quantitative analysis in cleared tissues
Image analysis/automation experience (e.g., Fiji/ImageJ, Python batch processing, napari; basic ML/DL toolchains)
Advantageous but not required: FELASA B, animal experiment coordination, VR-based annotation tools / 3D proofreading
MSc or PhD in life sciences, biomedical engineering, optical physics, or related field
Excellent scientific English, strong organization, service mindset, and ability to keep multiple collaborations moving