Master Thesis - Catalysis for NMR Hyperpolarization

The Hyperpolarization Methods research group at the Institute for Structural Biochemistry is open for applications for a Masters thesis project, in the field of catalytic chemistry. We use a method called parahydrogen‑induced polarization, which is a hyperpolarization technique to enhance the NMR/MRI signals of small molecules by four to five orders of magnitude, to enable exciting new applications in fields from medical diagnostics to materials characterization. We perform solution‑state hydrogenations using ruthenium catalysts to produce hyperpolarized molecules, and we are looking for a Masters student to investigate these catalysts and their mechanism of action using NMR and other analytical chemistry techniques.

Your Job:

This project will involve hands‑on experimental work to test different reaction conditions to develop an understanding of the ruthenium catalyst mechanisms, as well as the option to do some NMR theory and simulation work to predict NMR spectra and guide experiments.

In the research group you will work in an environment that combines the best parts of modern science with traditional academic values. You will carry out fast‑paced research on societally‑relevant topics, with individual support (especially for your personal well‑being) so you can grow as an individual. At the same time, you will have ample opportunity for acquiring knowledge, discussing science, and thinking creatively.

Your Profile:

• Current master studies in chemistry, biochemistry, materials science, or similar
• Basic experience with NMR and wet‑lab chemistry
• Willing to work within a multidisciplinary and collaborative research environment
• Curiosity and excitement to learn
• Good knowledge of spoken English

Our Offer:

We work on the very latest issues that impact our society and are offering you the chance to actively help in shaping the change! We support you in your work with:

• PERSONAL SUPERVISION: You can expect regular supervision and guidance from Dr. James Eills and a postdoc in the group. We will clearly define your project goals together and have regular meetings for project planning and scientific discussions
• MEANINGFUL GOALS: We aim to do socially impactful research: this project on the topic of ruthenium catalysis is aimed at creating novel contrast agents for molecular imaging to improve health
• PRACTICAL RELEVANCE: You will gain valuable practical experience alongside your studies and actively participate in interdisciplinary projects
• SCIENTIFIC ENVIRONMENT: You can expect excellent scientific equipment, modern technologies, and qualified support from experienced colleagues
• INTERNATIONAL ENVIRONMENT: We are an international research group and communicate in English. FZJ offers specific services for international employees if needed, e.g., through the International Advisory Service
• PUBLISHING: Our group regularly publishes research results in scientific journals, and we would aim to publish the results of this thesis project

If you are interested in this opportunity, please submit an application (in English), that includes a CV and cover letter, highlighting in particular how you meet the criteria for the position.

In addition to exciting tasks and a collegial working environment, we offer you much more:

We welcome applications from people with diverse backgrounds, e.g. in terms of age, gender, disability, sexual orientation / identity, and social, ethnic and religious origin. A diverse and inclusive working environment with equal opportunities in which everyone can realize their potential is important to us.

The following links provide further information on diversity and equal opportunities: and on specific support options:

We look forward to receiving your application. The job will be advertised until the position has been successfully filled. You should therefore submit your application as soon as possible.