Postdoc – Computational Functional Neuro-oncology (m/f/d)

wanted of the next possible date at the Division of Neuro-oncology at the Neurology Departement .

We are recruiting a Postdoctoral Researcher to join the research group of Computational Neuro-Oncology and Evolutionary Precision Medicine at Heidelberg University Hospital (UKHD), embedded within the Heidelberg neuro-oncology ecosystem (UKHD/DKFZ).

This position focuses on deciphering therapeutic strategies in CNS tumors by linking cellular states to functional vulnerabilities arising from their intrinsic molecular and phenotypic heterogeneity.

The project will integrate single-cell and bulk multi-omics data with functional perturbation datasets . Through integrative computational analyses, the aim is to move beyond descriptive characterization and develop quantitative frameworks that define actionable tumor states, their dependencies, and resistance mechanisms , ultimately enabling more precise and effective therapeutic strategies.

Your Tasks

• Lead analysis of single-cell and perturbation datasets across glioma patient derived models and tumor tissue
• Integrative analysis of multiomics and perturbation datasets
• Drive projects at the interface of computational biology, functional assays and clinical translation
• Contribute to shaping data-driven precision medicine strategies in neurooncology

Your Profile

• PhD in computational biology, bioinformatics, systems biology, computer science or related field
• Strong proficiency in Python and/ or R
• Experience in single cell omics analysis and multiomics data interpretation