Project Leader – Native Protein Purification (m/w/d)

Your profile

• Master’s or PhD in Biochemistry, Molecular Biology, Biotechnology, or related discipline.
• Strong practical experience in protein purification, particularly from native or human-derived sources.
• Proven expertise with chromatography systems (FPLC, HPLC) and protein characterization methods.
• Experience managing laboratory workflows or production activities.
• Strong troubleshooting skills and solution-driven mindset.
• Ability to balance hands‑on lab work with organizational responsibilities.
• Very good English communication skills (German is an advantage).

Why us?

• A permanent full‑time position (40 hours per week)
• A key leadership role in a specialized and growing protein‑focused environment
• State‑of‑the‑art purification and analytical infrastructure
• The opportunity to actively shape production processes and implement innovative ideas
• A collaborative and forward‑thinking scientific working environment in Heidelberg
• Flexible working hours from Monday to Friday within a motivated team and an excellent working atmosphere
• Company pension scheme, corporate sports activities, regular physiotherapy sessions, and discounted access to fitness studios
• Complimentary beverages and fresh fruit as our contribution to the well‑being of our team
• Conveniently accessible location with free parking

Your tasks

We are seeking a highly motivated and experienced Project Leader for Native Protein Purification to oversee and develop our purification activities focused on proteins isolated from human sources. This position combines hands‑on scientific expertise with production oversight and strategic development. The successful candidate will take ownership of purification workflows, ensure reliable production, and continuously improve processes while remaining open to innovative approaches and new technologies.

Key Responsibilities

• Scientific & Technical Leadership
  • Lead the purification of native proteins from human‑derived materials using advanced chromatographic techniques (affinity chromatography, ion exchange, size exclusion, hydrophobic interaction, FPLC, HPLC).
  • Design, optimize, and scale purification workflows to ensure high purity, yield, and reproducibility.
  • Establish and refine analytical methods including SDS‑PAGE, Western blotting, spectrophotometry, and mass spectrometry.
  • Evaluate and implement new purification technologies and strategies to enhance efficiency and quality.
• Production Management
  • Oversee day‑to‑day purification activities and ensure consistent, high‑quality protein production.
  • Plan production schedules, allocate resources, and monitor timelines.
  • Ensure proper preparation and quality control of buffers, reagents, and equipment.
  • Maintain compliance with safety, documentation, and regulatory standards.
  • Ensure meticulous record‑keeping and batch documentation.
• Team Coordination & Collaboration
  • Supervise and mentor technical staff involved in purification activities.
  • Foster a collaborative and solution‑oriented working environment.
  • Act as a key contact person for protein‑related projects within the organization.
  • Contribute ideas for expanding and strengthening the protein purification platform.

Does that sound convincing?

If you feel addressed and would like to become part of our company,

please upload your complete application via our application form, stating your salary expectations and earliest possible start date.

If you have any questions, you can also reach our HR department by phone at .

We look forward to hearing from you!