PhD student (d/f/m) in spatial omics in research towards precision medicine

The Berlin Institute of Health at Charité (BIH) is dedicated to biomedical translation. Its mission is to translate research findings into personalized prevention, diagnostics, and therapies to benefit patients and provide the scientific community with effective tools. With approximately 750 employees, the BIH specializes in translational method development, precision medicine, regenerative therapies, and biomedical data science. Closely integrated with Charité, the BIH promotes excellent research and facilitates the accelerated transfer of new discoveries into clinical practice through its supporting platforms and programs. Through these efforts, the BIH builds strong partnerships and fosters innovation-driven medicine in both national and international contexts.

For Prof. Dr. Christian Conrad’s team, we are looking for a PhD student in part-time (25.03 h/week) for a period of 3 years.

Genetic sequencing is mainly driven by fluorescence imaging. In the advent of spatial imaging and in situ sequencing directly on cells and human tissues, the group of Prof. Christian Conrad aims to apply latest deep learning and microscopic automation for translational medicine and molecular pathology. This includes fast optical imaging, single cell sequencing, machine learning and describes well the foci of the intelligent imaging group to study and improve patient care at Charité – BIH Center of Digital Health.

Tasks & Responsibilities

Translational clinical research of organ specific, cancer, and cardio-vascular topics
Planning, preparing and conducting experiments
Methods development in the spatial omics and tissue pathology
Collaborative bioinformatics analysis of single-cell sequencing and spatial omics data
Present data at international conferences and by publishing results in international peer-reviewed journals

Qualifications

Master's degree (Diploma or comparable) in life sciences
Strong background in molecular biology, medicine, biochemistry, biophysics, bioinformatics or related
Interdisciplinary focus in molecular biology, microscopy/imaging and/or bioinformatics
Programming skills or solid experience with deep learning methodologies is an advantage
Great interest in methods development
Excellent written and spoken English skills
Willingness to independently coordinate project-specific tasks and processes
Strong teamwork and collaboration skills

What we offer

A varied job in a forward-looking research institute
Pay group E13 TVöD VKA-K
Additional benefits customary in the public sector (including annual special payment, company pension scheme (VBL), capital-forming benefits)
Flexible working hours and the option of working remote
30 vacation days per year (with a five-day week)
Various support offers to balance work and family life (childcare, cooperation with voiio)
Training and further education opportunities
Mobile citizens' office on site
Corporate benefits (travel, leisure, shopping, etc.), Wellhub, JobRad
Easily accessible and attractive workplace at the Rahel Hirsch Center for Translational Medicine, Luisenstr. 65, 10117 Berlin

We live diversity! We welcome applications from people with diverse backgrounds, regardless of gender, nationality, ethnic and social origin, religion and ideology, disability, age, sexual orientation and identity. Applications from women are expressly encouraged. Severely disabled and equivalent applicants will be given special consideration if they have the same qualifications and suitability. We believe that diverse teams representing a wide range of experiences, perspectives and backgrounds enrich our research and work.

Proof of measles immunity / measles vaccination is a prerequisite for employment for those born after 1970.

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Berliner Institut für Gesundheitsforschung (BIG) - Berlin Institute of Health (BIH)