Primogene is an innovative biotech company developing advanced bioprocesses for the production of functional ingredients. We support human health through all stages of life and across industries including nutrition, pharma, and personal care.

About the role

As a Biocatalysis Scientist, your primary responsibility is the design, establishment, and optimization of enzyme-based reaction systems, with a strong focus on multi-enzyme cascades. You will work hands-on on building and improving robust, high-performing enzymatic reactions and cascade systems. Your role is centered on enzyme development and enzyme cascade optimization, from early-stage concept through scalable, industrially relevant enzymatic systems.

Key responsibilities

Enzyme development, including screening, selection, and characterization
Establishment and optimization of multi-enzyme cascades
Optimization of enzymatic reactions with respect to kinetics, stoichiometry, pH, temperature, cofactors, and operational stability
Development and implementation of one-pot and cascade reactions
Identification and resolution of bottlenecks within enzyme and cascade systems, including yield, productivity, and robustness limitations
Development and implementation of cofactor and co-substrate regeneration strategies

Qualifications

You should bring

PhD in Biochemistry, Biotechnology, Enzymology, Biocatalysis, or a closely related field
Strong hands-on experience in biocatalysis and enzymatic reaction development
Demonstrated experience with multi-enzyme systems and/or enzyme cascades
Solid understanding of enzymology, enzyme kinetics, and reaction engineering
Proven ability to design, execute, and interpret experimental work independently
Experience developing robust enzymatic systems beyond proof-of-concept (lab-scale or larger)

What we offer

Work on innovative technologies with real-world impact.
Work on challenging topics and cutting-edge science.
Contribution to solving highly important problems in human nutrition and health.
Steep learning curve with huge potential for personal and professional growth.
Dynamic team with a collaborative and entrepreneurial team culture.
Amazing team and colleagues

Primogene GmbH