Fachbereich Biologie, Chemie, Pharmazie - Institut für Biologie Neurogenetik - Neuro Cure Proje[...]

Serotonin–Glia Interactions in Metabolic Control and Feeding Behaviour in Drosophila NeuroCure Cluster of Excellence, Berlin. We are seeking a motivated PhD candidate to join our research team at the NeuroCure Cluster of Excellence in Berlin. The project investigates how serotonin–glia interactions regulate metabolic homeostasis and feeding behaviour using Drosophila melanogaster.

Research Field

In my research group, we investigate how the brain stores information as long-term memory. We use the fruit fly Drosophila melanogaster as a model organism, which allows us to analyze the neuronal and molecular mechanisms underlying memory formation with high precision.

A particular focus of our work is the role of neuromodulation. We are especially interested in how neuromodulatory signals – such as serotonin – influence whether and under which conditions memories are stored long-term. In addition, we study how the physiological state of the organism and other behaviours, such as feeding or stress, modulate memory formation.

Project

Job description

Energy balance and feeding behaviour are controlled by neuromodulatory systems. Serotonin is a key regulator of metabolic state and behaviour, but its interactions with glial cells remain poorly understood. This project aims to uncover the cellular and molecular mechanisms linking serotonergic signalling and glial function in metabolic control.

The position is limited to one year, as it is funded through time-limited project funding and tied to a defined research project.

The doctoral researcher will use genetic, behavioural, imaging, neurobiological, and computational approaches in Drosophila within a collaborative and interdisciplinary research environment.

Requirements

Completed university degree (M.Sc. or Diploma) in neuroscience, biology, molecular biology, bioinformatics, or a related field.

Desirable

• Experience working with Drosophila melanogaster
• Background in neurobiology
• Strong motivation for experimental research and data analysis
• Interest in interdisciplinary collaboration
• Excellent English and German communication skills
• Experience in genetics, imaging, behavioural analysis, molecular techniques, or computational/bioinformatic analysis is an advantage but not required.