PhD - Development of a Novel Lab-on-a-Chip Component for the Analysis and Sorting of Single Cells

Join a Bosch research project to develop a novel image-based DEP chip for single-cell analysis and sorting. You will advance automated, high-throughput multi-omics workflows using CMOS-compatible semiconductor fabrication. The role blends microfluidics, MEMS, and optical signal processing to push the limits of chip miniaturization and integration. You will design, fabricate, and validate a demonstrator that operates in physiological media, contributing to scalable life-sciences diagnostics. This position offers hands-on experimentation and cross-disciplinary collaboration within a mission-driven research environment.

• develop and evaluate DEP chip concepts for single-cell isolation and analysis
• determine robust electrical, microfluidic, and thermal operating parameters
• investigate chip miniaturization limits and CMOS-compatible manufacturing routes
• design and fabricate a functional demonstrator using semiconductor processes
• integrate the demonstrator into a microfluidic system
• characterize the prototype and perform proof-of-concept experiments with living cells
• perform experiments across all operating modes using representative bioassays
• document results and communicate research findings clearly

• Master in Electrical Engineering, Microsystems Engineering, Biomedical Engineering, Physics, or related field
• strong knowledge of classical MEMS, microfluidics, and lab-on-chip systems
• experience in microfluidic and electrical design for lab-on-chip applications
• ability to model microscale cell interactions and to process optical signals
• experience with cleanroom processes; knowledge of oncology advantageous
• proactive, collaborative, and able to conduct experiments independently
• proficiency in German and English (spoken and written)

• clear communication
• curiosity and initiative
• structured, goal-oriented work approach
• microfluidics
• electrical design for lab-on-chip
• MEMS