PhD position at Molecular Virology – Replication and pathogenesis of hepatitis A virus in advan[...]

wanted for the next possible date at the department of infectious diseases , molecular virology .

Join our international team as PhD student (m/f/d).

Our laboratory is dedicated to understanding of replication, innate immune response, treatment and pathogenesis of positive strand RNA viruses, with a focus on hepatotropic and gastrointestinal diseases (currently hepatitis C virus, hepatitis A virus and noroviruses).

Your tasks

The Lohmann Lab is seeking a highly motivated and collaborative PhD student to join our DFG-funded research project within the collaborative research consortium TRR179, aiming at the understanding of persistence and clearance of hepatotropic viruses. The project will focus on the characterization of two novel HAV molecular clones in cell culture and in animal models (in collaboration). We will implement immortalized cell lines as well as organoid models to understand HAV replication, pathogenesis and spread in gut and liver. The project further aims at identifying molecular determinants of HAV cell culture adaptation with a special focus on the nonstructural protein 2B. The candidate should have a strong background and interest in molecular biology and microscopy techniques, as well as in virus-host interactions.

Your profile

• Master degree in natural sciences
• Experience in microscopy
• To work accurately and being able to conduct independent research, but also enjoying to work in an international and interdisciplinary environment

Über uns

For further information please contact Prof. Dr. Volker Lohmann via e-mail.

Applications will be accepted until direct online.