Postdoctoral Researcher (d/w/m) in Population ‘omics and Pharmacoepidemiology

Postdoctoral Researcher (d/w/m)

Location: BIH Berlin Mitte, Charité, Berlin

Work schedule: Full‑time or part‑time (minimum 30 h/week).

Employment period: Limited contract until 28 February 2029.

Start date: As soon as possible.

Salary: Pay group E13 according to TVöD VKA‑K.

Job Overview

Position funded by the ERC Starting Grant “GenDrug”, aiming to integrate large‑scale genomic and real‑world clinical data to discover new drug targets.

Responsibilities

• Analyze blood‑based omics data (genomics, proteomics, metabolomics) from large cohorts such as UK Biobank and drug intervention studies.
• Investigate medication effects on blood biomarkers and clinical outcomes, incorporating pharmacogenetic analyses.
• Develop and apply statistical and computational methods—including causal inference and machine learning—to link multi‑omic variation with drug response and disease phenotypes.
• Build and maintain high‑throughput analysis pipelines and computational infrastructure using R (and Python), and work in HPC/cloud environments.
• Create interactive data‑visualization tools such as R Shiny apps to facilitate result exploration.
• Prepare scientific publications and figures, and present findings at conferences and seminars.
• Integrate individual‑level data analysis with publicly available results and databases through genome‑wide meta‑analysis or knowledge‑graph integration.
• Supervise and mentor junior researchers and students in data‑analysis projects.

Qualifications

• PhD in genomics, statistical genomics, genetic epidemiology, or a closely related discipline.
• Stage‑appropriate track record of high‑impact research and publications in genomics, multi‑omics, and/or pharmacoepidemiology.
• Demonstrable experience in several areas: generation/analysis of high‑throughput omics data; genome‑scale association analyses using whole‑genome or whole‑exome sequencing data; variant annotation; implementation and benchmarking of machine‑learning techniques in population‑scale omics settings with high clinical class imbalance; biological inference and clinical translation; HPC or cloud computing skills; proficiency in the English language.
• Proficiency in computational genomics and high‑throughput data processing.
• Strong analytical and translational mindset tailored to urgent clinical needs.

Benefits

• Varied job in a forward‑looking research institute.
• Annual salary (gross) for a full‑time position without special or additional payments, with collective agreement according to TVöD VKA‑K.
• Additional public‑sector benefits: annual special payment, company pension scheme (VBL), capital‑forming benefits.
• Flexible working hours and option to work remotely.
• 30 vacation days per year (five‑day week).
• Support to balance work and family life (childcare options, collaboration with voiio).
• Extensive training and further education opportunities.
• Mobile office on site and corporate benefits (travel, leisure, shopping, Charité Gympass, JobRad).
• Excellent accessibility at the Rahel Hirsch Center for Translational Medicine, Luisenstr. 65, 10117 Berlin.

Diversity & Inclusion

We welcome applications from people with diverse backgrounds, regardless of gender, nationality, ethnicity, religion, age, disability, sexual orientation and identity. Applications from women are specifically encouraged. Severely disabled and equivalent applicants will receive special consideration if they have the necessary qualifications.