Research Assistant (Ph.D. candidate) (f/m/d) in the field of Life Sciences (cardiac metabolism)

The

Research Assistant (Ph.D. candidate) (f/m/d) in the field of Life Sciences (cardiac metabolism)

Operational area: Department of Cardiology, Angiology, and Internal Medicine Intensive Care (Medical Clinic I) -experimental Cardiology - research group AG Möllmann/Prof. N. Marx

Working hours: 65% (25,03 hours/week) of the full working hours in the collective agreement (currently 38.5 hours/week)
Duration/Term of employment : the position is limited till in accordance with the WissZeitVG (German Academic Fixed-Term Contract Act) with option of prolongation. The successful applicant will be encouraged and supported to achieve a doctoral degree.
Start date:
Remuneration/Rates : EG 13 (TV-L)

Our research group consists of a combination of scientists and practicing cardiologists, which facilitates the integration of basic and clinical research. This project focuses on the impact of systemic diseases on oral and maxillofacial health. In particular, it is known that conditions such as cardiovascular disease or diabetes can impair periodontal remodeling and promote the progression of degenerative processes. However, the underlying mechanisms and the effects on the upper and lower jaws are not yet fully understood. Changes in the periodontium and alveolar bone can lead to bone loss, root resorption, and ultimately tooth loss. A particular focus is on the relationship between heart failure and inflammatory periodontal diseases, as there is evidence of a shared pro-inflammatory mechanism. The goal is to better understand the molecular basis of these interactions in order to develop innovative therapeutic approaches and to sustainably improve the effectiveness of dental and orthodontic treatments for affected patients.

Tasks:

• Assisting with or conducting animal experiments involving mice
  • Caring for and monitoring mice (checking, weighing and feeding them)
  • Assisting with blood collection and metabolic testing
• Independently performing laboratory work
  • Cell culture work
  • histological analyses 
  • Molecular and biochemical analyses (e.g. Western blot and real-time PCR)
  • Isolation of primary cells and mitochondria

Profile:

• A completed master’s degree in a science subject, e.g. biotechnology, biomedicine, chemistry or a comparable field
• Practical experience of standard techniques in protein chemistry and molecular biology
• The ability to work well in a team and independently, with a precise and open work style, as well as organisational skills
•  A strong willingness to learn new skills
• Desirable:
  
  • FELASA B certificate
  • Proficiency in data processing and word processing
  • English proficiency (Level B2)
• An individual who is self-motivated, independent and team-oriented, with a knack for structured, detail-oriented work, and strong communication and teamwork skills
• Interest in and willingness to take on new responsibilities
• The motivation to contribute actively to the development of the project

Why choose us?

We offer…

• 30 days of vacation
• A bonus of 3,000 euros for employees who help recruit employees in the care sector
• An attractive company pension scheme from VBL
• Education opportunities , including updating and upgrading 
• Access to public transport
• In-house kindergarten (places subject to availability)
• Staff residences (places subject to availability and by arrangement)
• An onboarding app for new employees
• Extended opening hours in the staff restaurant