Senior / Principal Scientist - Preclinical PK/PD Modelling and Simulation

The Position
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Unleash your passion, embrace the science, and make an impact.
As a Senior/ Principal Scientist in Global Preclinical PK/PD Modelling within 'Global Drug Discovery Sciences', you will be an integral part of our multidisciplinary research teams and drive model-informed decision making in and beyond the drug discovery stage. You will live our "learn-and-confirm" mentality and strongly interact with our drug metabolism and pharmacokinetic (DMPK), NBE pharmacokinetic, Medicinal Chemistry, Biotherapeutics Discovery, as well as biomarker and pharmacology disciplines within our international project teams.
The mission of our Research Department 'Global Drug Discovery Sciences' is to find high-quality first-in-class drug candidates. Our ambition is to make significant contributions to breakthrough therapeutic concepts by providing excellence in drug screening, profiling, optimization, and translation to ensure seamless transition of drug candidates to Development. Join Global Preclinical PK/PD Modelling and Simulation at the company's largest Research & Development site.
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This position can be filled either as Senior Scientist or Principal Scientist.
This position has a hybrid setup with approximately 3-4 days per week on site.
Tasks & responsibilities
In your new role, you will perform high-quality PK/PD modelling and simulation analyses to support research projects by contributing to informative study designs of preclinical PK and/or PD experiments, by performing high-quality human PK and dose predictions and by contributing to strategies to better understand the PK/PD relations of our candidate drugs.
You will contribute to achieving modelling-related goals for Discovery Research by representing Preclinical PK/PD Modelling in international Research Project Teams.
Moreover, you will represent and coordinate Research DMPK or NBE PK in international Research Project Teams. This includes establishing and maintaining external collaborations and supporting licensing activities.
Additional tasks & responsibilities as Principal Scientist
As a Principal Scientist, you will lead the coordination of all Drug Discovery Sciences disciplines, which include Research DMPK, NBE PK, CMC, Bioanalytic, and Biomarker functions, in international Research Project Teams.
You will shape and implement PK/PD modelling strategies and approaches for specific Therapeutic Areas / indications, including the definition of modelling-related goals for Discovery Research.
Furthermore, you will coach and support the development of (junior) research scientists.
Requirements
PhD in a field related to (preclinical) PK/PD modelling with several years of relevant experience in PK/PD modelling and simulation; Industry experience is considered beneficial
A solid knowledge in biology, DMPK and/or pharmacology
Proven skills in PK, PK/PD, PBPK, and / or longitudinal disease modelling
Proficiency in (statistical) programming languages and pharmacometric tools e.g., R, MATLAB, Phoenix WinNonLin, NONMEM
Authentic, enthusiastic, cooperative, and creative personality with excellent communication skills in English
Additional requirements as Principal Scientist
PhD with long-term experience in a field related to (preclinical) PK/PD modelling, pharmacometrics, applied mathematics, systems biology, bioinformatics or similar; Industry experience is considered beneficial
In-depth understanding of (preclinical) PK/PD modelling and simulation, as well as pharmacology and DMPK- and/or NBE PK- related topics
Experience in working in and leading matrix-style project teams
Applications from people with severe disabilities are warmly welcomed. In cases of equal qualifications, such applicants will be given preferential consideration in the selection process.
Ready to contact us?
If you have any questions about the job posting or process - please contact our HR Direct Team, Tel: or via mail:

Recruitment process:
Step 1: Online application - The job posting is presumably online until June 15th, 2026.
Step 2: Virtual meeting mid until end of June
Step 3: On-site interviews beginning of July
Please submit your application documents in English.
Unser Unternehmen
Bei Boehringer Ingelheim entwickeln wir bahnbrechende Therapien, die das Leben von Mensch und Tier verbessern. Als 1885 gegründetes und seitdem im Familienbesitz befindliches Unternehmen nehmen wir eine langfristige Perspektive ein. Mit 52.000 Mitarbeitenden weltweit setzen wir unsere Ziele um und fördern dabei eine vielfältige, gemeinschaftliche und inklusive Unternehmenskultur. Wir sind überzeugt: Mit talentierten und ambitionierten Mitarbeitenden und ihrer Leidenschaft für Innovationen heben wir die Grenzen des Erreichbaren immer wieder auf.
Warum Boehringer Ingelheim?
Bei uns können Sie wachsen, zusammenarbeiten, innovativ sein und Leben verbessern.
Wir bieten Ihnen herausfordernde Tätigkeiten in einem respektvollen und kollegialen globalen Arbeitsumfeld mit einer Vielzahl von auf Innovation ausgerichteten Denkweisen und Methoden. Darüber hinaus sind für uns Qualifizierung und Entwicklung für alle Mitarbeitenden von zentraler Bedeutung, denn Ihr Wachstum ist unser Wachstum.
Boehringer Ingelheim ist ein globaler Arbeitgeber, der sich für Chancengleichheit einsetzt, und ist stolz auf seine vielfältige und inklusive Kultur. Wir begrüßen die Vielfalt von Perspektiven und streben nach einem inklusiven Umfeld, wovon unsere Mitarbeiter*innen, Patienten*innen und Communitys profitieren. xvbsvpc
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