Director of Computational Innovation Neuroscience & Mental Health

22nd October, 2025

Retained Search | Director of Computational Innovation - Neuroscience & Mental Health

KEMIO Consulting has been exclusively retained to identify a visionary Director of Computational Biology to lead computational strategy within the Neuroscience & Mental Health (N&MH) Therapeutic Area at a global pharmaceutical leader.

This is a pivotal and high-visibility role shaping how next-generation mental health therapeutics are discovered - not by addressing disease-level pathology, but by targeting symptoms and patient stratification to enable precision psychiatry.

The Mission

Traditional neuropsychiatric drug development is limited not by targets, but by the inability to predict who will respond. This role transforms that paradigm.

You will lead an integrated computational effort spanning early discovery → translational medicine → Phase IIb , building a framework for biotypes, digital/imaging biomarkers, and patient subgroups that link biological signal to therapeutic outcome.

You will inspire and lead

• Computational strategy across the Neuroscience & Mental Health TA
• Multimodal integration: genetics/omics + imaging (EEG/MEG/fMRI) + digital/activity data
• Biomarker and patient stratification science for precision N&MH
• Scientific leadership across translational and clinical interfaces
• Team scaling (internal FTEs + CRO/innovation partners)
• Impact on flagship programmes (e.g., PRISM-2) and New Therapeutic Concepts (NTCs)

What Success Looks Like

• Turning heterogeneous patient populations into defined, stratifiable biotypes
• Developing clinically relevant biomarkers for motivation, cognition, emotional imbalance, impulsivity, and related symptom domains
• Building a computational function that changes decision-making in the clinic
• Partnering with therapeutic and clinical leaders as a true peer - not as a service function

The Person We Are Looking For

Scientific & Technical

• Deep experience in computational neuroscience / computational biology
• Strong ML/AI capability applied to imaging or activity-based biomarkers
• Fluent in multimodal data fusion (omics + imaging + behavioural/digital)

Translational Mindset

• Thinks in patient outcomes, not abstract modelling
• Understands the difference between symptom targeting vs. disorder pathology
• Comfortable with real-world data constraints in psychiatric indications

Leadership

• Can set computational direction and influence at TA leadership level
• Builds high-performing teams and external networks
• Operates credibly across research, translational medicine and clinical development

This role will resonate with someone who:

• Has worked at the interface of computational science and patient biology
• Has either exposure to clinical / neuroimaging studies or hybrid clinical-scientific training
• Wants to drive the future model of personalised psychiatry
• Is motivated by scientific complexity + real-world patient impact

Contact

KEMIO Consulting is leading this retained search and would welcome confidential discussions with senior candidates. Please apply or get in touch with Eugene @ KEMIO Consulting to discuss this opportunity in more detail.

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