PostDoc (all genders) for Immunology

Main Tasks

At the Hamburg Center for Translational Immunology (HCTI) within the University Medical Center Hamburg-Eppendorf (UKE), we are actively seeking highly motivated postdoctoral candidates with a robust background in immunology as part of the Institute for Inflammation and Carcinogenesis (UKE–HCTI–Startseite). Our research focus is on investigating the fundamental molecular and cellular mechanisms of T cell biology. Specifically, we explore how T cells adapt to environmental changes and ultimately contribute to either mediating physiological responses or engaging in pathological tissue-damaging processes (Vesely et al., Cell (2019), Zhao Yu et al., Science Immunology (2021), Tintelnot J. et al., Nature (2023), Siracusa F. et al., Nature Imm. (2023), and Liebold I. et al Science (2024)). We follow a circular research approach that begins with a unique collection of human samples and multi-omics analyses, proceeds to mechanistic studies in mice, and returns to validation in humans—including clinical trials—to generate clinically relevant insights (Tintelnot J. et al., Nature 2023; Siracusa F. et al., Nature Immunology 2023). In the years ahead, we aim to delve deeply into the complex interactions between environmental factors and the immune system. In particular, we would like to investigate the mechanisms that regulate the response of intestinal and extra‑intestinal CD4⁺ T cells to different diets, focusing on how these responses either promote protective, tolerogenic responses or pathogenic, pro‑inflammatory reactions; these may occur directly or indirectly via the modulation of the bio‑availability of microbial metabolites. One of our main focuses in this context is the feto‑maternal cellular adaptation to dietary interventions, as these processes can critically influence both maternal health and offspring development. Studying such mechanisms will provide valuable insights for developing improved treatments and advancing personalized nutrition and medicine. The institute is funded by DFG and ERC grants, providing a unique opportunity to access a combination of state‑of‑the‑art techniques and multi‑omics human and mouse data to answer key biological questions.

Position is initially limited until for project‑related reasons (third‑party funding).

Profile

• Completed academic studies in relevant subjects, including biology, biochemistry, human biology, medicine or related subjects
• Applicants must hold a PhD, MD, or an equivalent degree
• Candidates should have expertise and commitment to experimental immunology

Immunity Status

Please note that employment is contingent upon proof of immunization or immunity against the measles virus, in accordance with applicable legal and medical requirements. Documentation (e.g., vaccination certificate) must be provided before employment begins.

Our Offer

• International and multidisciplinary environment at the University Medical Center Hamburg‑Eppendorf, a leading institution in Europe (Germany)
• Access to several sophisticated mouse models and next‑generation sequencing platforms (e.g., 10X) and the possibility to learn state‑of‑the‑art aspects of bioinformatics analysis
• Access to the institution's soft skills program, including training in presenting skills and scientific writing, as well as career‑oriented courses
• Career mentorship focused on building the best possible career within and outside academia
• Weekly scientific exchange through lab meetings and journal clubs
• Attractive compensation according to TVöD/VKA
• Secure employment with meaningful work and respectful collaboration
• Comprehensive onboarding and open knowledge exchange within the team
• Extensive training and further education programs at our UKE Academy for Education and Careers
• Opportunities to contribute to our “UKE INside” personnel policy through cross‑professional and cross‑hierarchical projects
• Sustainable travel: subsidies for the Deutschlandticket as a job ticket, and Dr. Bike bicycle service
• Family‑friendly working environment: cooperation on childcare, free vacation childcare, advice for employees with relatives in need of care
• Excellent health, wellness, and sports programs
• A wide range of dining options in our staff restaurant, with additional choices available at the “Health Kitchen” cafés, bistros, and an on‑site supermarket

Contact

Dana Klatt

Recruiting Team
+49 (0)

About Us

We live diversity and value variety. We offer a work environment that provides equal opportunities regardless of age, gender, sexual identity, disability, ethnic and social origin, or religion. This is confirmed by our accession to the Charter of Diversity. We explicitly aim to increase the proportion of women in management positions, especially among scientific personnel in research and teaching. Women with equal qualifications will be given priority. The same applies in the case of under‑representation of one gender in the advertised area. Persons with severe disabilities with equal aptitude, competence, and professional performance will be given priority.

Learn more about "Diversity at UKE" here.