Senior Manager Medical Affairs, Metabolic Disorders Science

Position Summary

ultra dedicated – Your biggest challenges yield rare possibilities

This role supports the development and execution of medical strategies in Japan, leveraging nutrition science or biochemistry and/or pathologic nutrition or a related field, expertise to guide research planning and evidence generation. The position primarily supports Ultragenyx’s development stages and commercialized products in Japan.

Work Model

Remote: Officially documented as working full-time from home, with travel to Ultragenyx's offices or other locations on occasion as needed.

Responsibilities

1. Develop and execute medical strategies focused on the program’s mechanism of action, including dietary therapy–related mechanisms, within the field of metabolic disorders.
2. Lead and provide scientific input to support field medical team and evidence generation from a metabolic disorders perspective.
3. Serve as a subject matter expert and strategic partner to Japan Medical Directors, leading the generation of medical strategies as the biochemical and pathologic nutrition expert.
4. Collect and share up‑to‑date scientific information on nutrition and metabolic disorders.
5. Analyze and report findings from scientific literature and conference proceedings.
6. Support the development of educational materials and internal training related to metabolic disorders.
7. Ensure all activities comply with company policies, SOPs, and relevant compliance standards.
8. Support scientific information exchange and insight gathering at congresses and external events as needed.

Requirements

1. Advanced degree (PhD or MS) in Nutrition Science, biochemistry and/or pathologic nutrition or a related field, with research experience required.
2. Research experience in Nutrition Science and/or Biochemistry and/or metabolic disorders.
3. 3+ years post‑graduate experience in pharmaceutical industry, research or other relevant experience required.
4. Clinical experience as a Registered Dietitian (e.g., patient counseling, nutrition management, or practical work in clinical settings) is preferred.
5. Experience in rare diseases is a plus.
6. Native level Japanese and business level English proficiency (reading, writing, and communication).
7. Strong communication and teamwork skills to collaborate effectively with internal and external stakeholders.
8. Demonstrated hands‑on experience in analyzing, summarizing, and presenting scientific content.
9. Ability to work independently and manage multiple priorities.
10. Primarily remote or office based; able to support limited field activities (e.g., domestic travel and congress participation) as needed.

Benefits

• Generous vacation time and public holidays observed by the company
• Volunteer days
• Long‑term incentive and Employee Stock Purchase Plans or equivalent offerings
• Employee wellbeing benefits
• Fitness reimbursement
• Tuition sponsoring
• Professional development plans
• Benefits vary by region and country

Equal Opportunity Employer Statement

Ultragenyx Pharmaceutical is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status and any other status or classification protected by applicable federal, state and/or local laws. Reasonable accommodation will be provided for all protected statuses or classifications protected by applicable law, including individuals with disabilities, disabled veterans, for pregnancy, childbirth, and related medical conditions, and based on sincerely held religious beliefs. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, you may contact Talent Acquisition by emailing

Legal Notice

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.