Principal Clinical Scientist

About The Role

What if your career's worth of clinical trial expertise could directly shape how AI understands and reasons about medical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor into AI-driven research workflows — helping ensure the clinical data powering next-generation AI systems meets the exacting standards of real-world regulatory submissions.

This is a fully remote, flexible contract role built for experienced clinical scientists who want to do meaningful work at the frontier of AI and biomedical research.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation
• Interpret and audit clinical trial results to ensure accuracy, consistency, and alignment with regulatory standards (FDA, EMA, or equivalent)
• Evaluate AI-generated clinical analyses for scientific soundness and regulatory relevance
• Provide expert feedback that directly improves how AI models reason about clinical trial data, outcomes, and evidence
• Work independently and asynchronously — fully on your own schedule

Who You Are

• Senior-level clinical scientist with hands-on experience designing trial protocols for regulatory submission
• Deep expertise interpreting clinical data for regulatory agencies such as the FDA, EMA, or equivalent bodies
• Strong grounding in clinical research methodology, biostatistics, or translational science
• Naturally rigorous and detail-oriented — you hold clinical data to the highest standard
• Clear and precise written communicator who can translate complex findings into structured, actionable feedback

Nice to Have

• Prior experience with data annotation, data quality review, or evaluation systems
• Familiarity with AI tools or clinical AI applications as a practitioner or evaluator
• Background in drug development, medical devices, or health technology assessment

Why Join Us

• Work directly on frontier AI systems that are reshaping how clinical and biomedical research is conducted
• Influence how AI understands, evaluates, and reasons about real-world clinical evidence
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, expert-level work
• Collaborate with world-leading AI research teams and labs on cutting-edge projects
• Potential for ongoing work and contract extension as new projects launch