PhD position Biomathematics – Systems Biology of Allergic Reactions

PhD position Biomathematics – Systems Biology of Allergic Reactions

When: 26 Feb 2025

Location: Bonn Center for Mathematical Life Sciences, Germany

The mammalian immune response depends on the interaction and collaboration of many highly individual cells. The group of Prof. Dr. Kevin Thurley uses mathematical modeling and data analysis tools to quantify and rationalize immune cell dynamics in the context of clinical manifestations such as inflammation and cancer. Prof. Dr. Natalija Novak is the director of the Department of Dermatology, and her primary research interest is the pathophysiology of atopic dermatitis. The groups are integrated into both the ImmunoSensation and the Hausdorff Mathematics Clusters of Excellence, an exceptional environment for our interdisciplinary research program.

In the available Ph.D. project, we will design and analyze data-driven models of cell-cell communication networks in the context of atopic dermatitis and allergic drug reactions, based on an established experimental system and patient-derived data sets.

The project may comprise deterministic, stochastic and spatial modelling techniques as well as analysis of single-cell sequencing and high-content imaging data, thus offering ample opportunity for expert training in state-of-the-art systems immunology.

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