Senior / Principal Scientist Pharmacometrics

Senior / Principal Scientist Pharmacometrics

Join to apply for the Senior / Principal Scientist Pharmacometrics role at Boehringer Ingelheim

The Position

Are you passionate about applying your pharmacometric skills, strategic thinking, and practical experience in data analysis? Would you like to join cross‑functional clinical development teams and expand your influence and deepen your knowledge in pharmacometric approaches?

The Senior/ Principal Scientist - Pharmacometrics will independently perform high‑quality pharmacometric (PMx) analyses on an asset and study level essential for internal decision making and successful approval. The incumbent will represent Clinical Pharmacology/PMx in (pre)‑clinical development teams, develop PMx strategies and author PMx documents.

The position follows a hybrid working model with regular on‑site presence. This position can be filled either as Senior Scientist or Principal Scientist in Ingelheim or Biberach.

Tasks & Responsibilities

• As Senior Scientist, develop the pharmacometric strategy and identify opportunities where pharmacometric approaches can further the understanding of pharmacological activity, efficacy and safety of a drug.
• Act as the PMx lead in cross‑functional teams, responsible for PMx data and data analysis strategy and advising (early) clinical development teams on MIDD opportunities and limitations.
• Plan and execute relevant pharmacometric analyses to support internal decision making, disease understanding and successful approval.
• Ensure timely delivery of analysis‑related documentation (e.g., dataset specification, analysis plans, and reports) and co‑author documents (e.g., asset evidence plan, pediatric investigational plan, submission documents).
• Organize and manage projects with external organizations such as CROs or academic institutions.
• Represent Clinical Pharmacology/PMx in internal initiatives and working/focus groups collaborating closely with other disciplines.

Additional tasks for the Principal Scientist role

• Act with a higher level of independence and provide consultancy and advice for other scientists and stakeholders as an internally and externally recognized scientist.
• Represent Clinical Pharmacology/PMx in internal and external initiatives/working groups such as focus groups in your area of expertise, across department initiatives, process harmonization, IMI calls, ISoP groups.

Requirements

• PhD, MD or master’s degree from an accredited institution in Pharmacometrics, Clinical Pharmacology, Pharmacy, Medicine, Mathematics, Biology, Statistics or relevant area of focus.
• First experience in Pharmacometrics in the pharmaceutical industry, regulatory agencies, or academia.
• Solid knowledge in applying PMx software (e.g., NONMEM, Monolix, R, PBPK software) and approaches (e.g., population pharmacokinetics, pharmacokinetics/pharmacodynamics, exposure response, disease progression modeling, model‑based meta‑analysis and PBPK).
• Basic knowledge in other data science fields, clinical pharmacology, clinical drug development, MID3, and regulatory guidelines. Additional knowledge in oncology, toxicology and DMPK, quantitative systems pharmacology, as well as applications of AI/ML in pharmacometrics/clinical pharmacology will be a plus.
• Strong team player, who is able to successfully act in the global context and with the ability to pro‑actively identify issues and solutions.
• Good interpersonal skills with the ability to interact effectively with people, internally and externally.

Additional requirements for the Principal Scientist role

• Multi‑years of relevant experience in Pharmacometrics in the pharmaceutical industry, CROs, regulatory agencies, or academia.
• Several years of relevant experience in working in (pre)‑clinical development teams.
• Broad knowledge in applying PMx software and approaches.
• Broad knowledge in other data science fields, clinical pharmacology, clinical drug development, MID3, and regulatory guidelines. Additional knowledge in oncology, toxicology and DMPK, quantitative systems pharmacology, as well as applications of AI/ML in pharmacometrics/clinical pharmacology will be a plus.

Ready to contact us?

If you have any questions about the job posting or process - please contact our HR Direct Team, Tel: +49 (0) or via mail:

Recruitment process:

1. Online application – The job posting is presumably online until November 2nd, 2025. Applications up to October 27th, 2025 are guaranteed to be considered.
2. Virtual meeting in the period from beginning till mid of November.
3. On‑site interviews end of November.

Seniority level

Mid‑Senior level

Employment type

Full‑time

Job function

Research, Analyst, and Information Technology

Industry

Pharmaceutical Manufacturing

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