Research Associate (gn*) in Molecular Tumor Biology

Research Associate (gn*) in Molecular Tumor Biology

Job Id: 12327

The Institute of Molecular Tumor Biology (IMTB), headed by Prof. Dr. Frank Rosenbauer, is an experimentally oriented medical research institute focused on understanding the molecular mechanisms of cell differentiation, tumor development, and immune cell function.

A major research focus is the role of transcription factors in hematopoietic cell fate regulation and their interaction with epigenetic mechanisms. We use state‑of‑the‑art approaches, including next‑generation sequencing, functional genetic screens, and transgenic model systems. Further information is available on our homepage and via our publications in leading journals such as Nature Immunology, Nature Genetics, The EMBO Journal, Blood, and others.

We are seeking a talented and highly motivated Postdoctoral Fellow to join our research team. The successful candidate will investigate the epigenetic and proteasomal regulation of neutrophil function. Neutrophils are the most abundant circulating leukocytes and represent the first line of defense against microbial infections. Because dysregulated neutrophil responses contribute to the pathogenesis of numerous immune‑mediated diseases, understanding the mechanisms that govern their activation is of considerable biological and clinical importance.

The project will integrate cutting‑edge omics technologies with state‑of‑the‑art disease models to elucidate how epigenetic and proteasomal pathways regulate neutrophil functions in the contexts of infection and cancer.

REQUIREMENTS

• A completed Ph.D. in a relevant field
• Experience with relevant methods and concepts in cellular immunology
• Hands‑on experience with cell and tissue cultures as well as common molecular biology techniques
• Basic proficiency in the R programming language
• Experience working with public omics datasets and repositories
• Experience working with laboratory mice is a plus
• Publication(s) in a leading journal in immunology, molecular biology, or a related field, including at least one research article authored as first author
• Excellent written and spoken English skills
• High motivation, willingness to learn, and team spirit
• Strong sense of responsibility, organizational skills, high reliability, and flexibility

This is a position in the wet lab, so applicants with a background solely in (bio)informatics will not be considered.

WE OFFER

• An internationally renowned and highly visible research environment within the globally unique TRR332 consortium on neutrophils, funded by the German Research Foundation (DFG), dedicated to advancing our understanding of neutrophil origin, fate, and function.
• An exciting field of work in innate immunology, an open‑minded team, and an attractive campus environment where you can pursue your professional interests in state‑of‑the‑art research laboratories and teaching facilities.
• Salary based on the collective bargaining agreement—pay grade TV‑L E13. Classification is determined based on relevant professional experience, and includes an annual bonus and a company pension plan (VBL).
• A wide range of continuing education and professional development opportunities to support your growth.
• A respectful and supportive work environment within a diverse, international team.
• Numerous support and counseling services regarding health or work‑life balance.
• Many other benefits such as sports programs, a commuter pass, company parties, a cafeteria, or emergency childcare.

Equal Opportunities

Equal opportunities are an integral part of our HR policy. UKM supports the compatibility of career and family life and has been certified as a family‑conscious employer since 2010. In principle, part‑time employment is possible. In areas where women are underrepresented, they will be given preferential consideration in accordance with statutory provisions, provided they have equal qualifications, aptitude, and professional performance. Applicants with severe disabilities will also be given preferential consideration under the same conditions and within the framework of legal regulations.