Scientist – MS Biomarker Research, Proteomics

Stellenbeschreibung:

Scientifically review requests for biomarker discovery and quantitation
Align the purpose and path forward with partners in project teams
Lead the design, execution, and analysis of proteomics experiments, including biomarker discovery, targeted quantification, PTM identification, and interactome determination
Use omics platforms for translational topics, NTC confirmation, functional validation, and mechanism-of-action elucidation
Generate and analyze proteomics samples
Operate and maintain various LC-MS systems
Advance scientific and proteomics workflows through innovative approaches
Educate and train Boehringer Ingelheim colleagues in proteomic analysis
Continue developing scientific and drug development expertise
Represent the scientific discipline in cross-functional teams and contribute to discovery portfolio opportunities

Requirements

Completed Master’s degree / PhD in mass spectrometry-based proteomics, biochemistry, pharmacology, or a related scientific discipline
Several years of relevant hands‑on experience with data‑independent acquisition (DIA) workflows on a Thermo Orbitrap Astral mass spectrometer
First insights into drug discovery programs within the pharma industry beneficial
Experience with state‑of‑the‑art proteomics workflows
Experience in sample preparation from cells and tissues for LC-MS analyses
First experience with characterizing disease‑relevant animal models for translational aspects is a plus
Solid understanding of biochemistry, molecular mechanisms, and pharmacology relevant to drug discovery
Conceptual understanding of biomarkers in drug discovery and development, paired with first experience in this field
Expertise in operating mass spectrometry platforms (Orbitrap, QTOF, etc.)
Expert understanding of respective analysis software
Analytical mindset and ability to work independently and collaboratively in an interdisciplinary research environment
Critical and creative thinking; self‑motivated to innovate
Excellent data analysis, data management, and presentation skills
Fluent written and spoken English
German language skills are a plus
Application documents must be submitted in English

Core Competencies

Demonstrates expertise in mass spectrometry‑based proteomics, including biomarker discovery and quantification, while effectively collaborating in cross‑functional teams to advance drug development initiatives. Proficient in operating and maintaining LC-MS systems and applying innovative approaches to proteomics workflows.